Recombinant Human ER alpha (N-His)

Product code: 32-9169

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Available Pack Size(s)

  •   500 µg

  •  50 µg

  • $1,690.00 

  • $679.00 

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Amount : 50 µg
Content : Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
AA sequence : Recombinant Human Estrogen receptor alpha is produced by our E.coli expression system and the target gene encoding Met1-Gln116 is expressed with a 6His tag at the N-terminus.
Alternative Name : Estrogen Receptor; ER; ER-Alpha; Estradiol Receptor; Nuclear Receptor Subfamily 3 Group A Member 1; ESR1; ESR; NR3A1
Source : E.coli;
Estrogen Receptor is a major ligand-activated transcription factor that belongs to the nuclear hormone receptor superfamily. It is widely expressed and acts as a strong activator of estrogen-responsive genes. Estrogen Receptor is composed of several domains essential for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are necessary for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
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