Recombinant Human Electron Transfer Flavoprotein Subunit beta/ETFB (N-6His)(Discontinued)
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| Amount : | 50 µg |
| Content : | Supplied as a 0.2 µm filtered solution of 20mM HEPES,150mM NaCl, pH 7.4. |
| Storage condition : | Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| AA sequence : | MNHKVHHHHHHMAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI |
Source: E. coli.
MW :29.2kD.
Recombinant Human ETFB is produced by our E.coli expression system and the target gene encoding Met1-Ile255 is expressed with a 6His tag at the N-terminus. Electron transfer flavoprotein subunit beta is a subunit of electron transfer flavoprotein, serves as a specific electron acceptor for several dehydrogenases. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Electron transfer flavoprotein subunit beta and alpha combine a heterodimer can binds 1 FAD per dimer. Defects in ETFB are the cause of glutaric aciduria type 2B (GA2B).
MW :29.2kD.
Recombinant Human ETFB is produced by our E.coli expression system and the target gene encoding Met1-Ile255 is expressed with a 6His tag at the N-terminus. Electron transfer flavoprotein subunit beta is a subunit of electron transfer flavoprotein, serves as a specific electron acceptor for several dehydrogenases. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Electron transfer flavoprotein subunit beta and alpha combine a heterodimer can binds 1 FAD per dimer. Defects in ETFB are the cause of glutaric aciduria type 2B (GA2B).
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Mitochondrion matrix |
| Post transnational modification: | Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from Acyl-CoA dehydrogenases. |
| Tissue Specificity: | Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. |
| BioGrid: | 108410. 35 interactions. |
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