Recombinant Human Deoxyhypusine Synthase/DHS (C-6His)
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Amount : | 50 µg |
Content : | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 20% Glycerol, pH 8.0. |
AA sequence : | Recombinant Human Deoxyhypusine Synthase is produced by our E.coli expression system and the target gene encoding Met1-Asp369 is expressed with a 6His tag at the C-terminus. |
Alternative Name : | Deoxyhypusine Synthase, DHS, DHPS, DS |
Source : E. coli;
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
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