Recombinant Human D-glucuronyl C5-epimerase (N-Flag-6His)(Discontinued)
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Amount : | 50 µg |
Content : | Supplied as a 0.2 µm filtered solution of 20 mM Tris,200mM NaCl,pH8.0 . |
Storage condition : | Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
AA sequence : | DYKDDDDKHHHHHHNKCSSDKAIQFPRRSSSGFRVDGFEKRAAASESNNYMNHVAKQQSEEAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN |
Source: Human Cells.
MW :68.7kD.
Recombinant Human D-glucuronyl C5-epimerase is produced by our Mammalian expression system and the target gene encoding Asn29-Asn617 is expressed with a 6His, Flag tag at the N-terminus. D-glucuronyl C5-epimerase is an enzyme that in humans is encoded by the GLCE gene. D-glucuronyl C5-epimerase converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
MW :68.7kD.
Recombinant Human D-glucuronyl C5-epimerase is produced by our Mammalian expression system and the target gene encoding Asn29-Asn617 is expressed with a 6His, Flag tag at the N-terminus. D-glucuronyl C5-epimerase is an enzyme that in humans is encoded by the GLCE gene. D-glucuronyl C5-epimerase converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Golgi apparatus membrane |
BioGrid: | 117501. 15 interactions. |
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