Recombinant Human CD112 Protein, mFc Tag
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| Amount : | 50 µg |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Uniprot ID : | Q92692 |
| Alternative Name : | NECTIN2? HVEB? PRR2? PVRL2? PVRR2 |
Molecular Characterization: CD112(Gln32-Gly360) mFc(Pro99-Lys330)
Molecular weight: The protein has a predicted molecular mass of 61.4 kDa after removal of the signal peptide.The apparent molecular mass of CD112-mFc is approximately 35-55 kDa due to glycosylation.
Description: Recombinant Human CD112 with C-terminal mouse Fc tag
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Molecular weight: The protein has a predicted molecular mass of 61.4 kDa after removal of the signal peptide.The apparent molecular mass of CD112-mFc is approximately 35-55 kDa due to glycosylation.
Description: Recombinant Human CD112 with C-terminal mouse Fc tag
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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