Recombinant Human CB1 protein with C-terminal human Fc

Product code: 32-17132

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50 µg
$498.00 

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Amount : 50 µg
Purification : The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage condition : Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
Expression Host : HEK293
The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide.The apparent molecular mass of CB1-hFc is approximately 55-70 kDa due to glycosylation.
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
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