Recombinant Human BCMA(Discontinued)
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| Amount : | 20 µg |
| Purification : | Purity: >= 98% by SDS-PAGE gel and HPLC analyses. |
| AA sequence : | AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA |
| Alternative Name : | B-Cell Maturation Antigen, TNFRSF17, BCM |
Source: E.coli
BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B cells and other B cell lines, and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid cytoplasmic domain. Recombinant soluble Human BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein.
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