Recombinant Anti-SARS-CoV-2 Nucleocapsid antibody (ABMX-004)
Fig-1: ELISA detection of Anti-SARS-CoV-2 Nucleocapsid antibody (ABMX-004) cat. no. 10-2007. An ELISA plate coated with 100 ng of Nucleocapsid protein (Abeomics, Cat. No. 21-1003) was incubated over night at 4C. Different concentrations of Anti-Nucleocapsid recombinant antibody (ABMX-004) was added to the plate. Goat anti-human FC HRP was used as detection antibody.
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| Amount : | 100 µg |
| Isotype : | Human IgG1 kappa |
| Purification : | Affinity purified |
| Content : | 0.5 mg/ml, 100 ug in sterile PBS |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | N |
| Uniprot ID : | P0DTC9 |
The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS- CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self- assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.
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