Recombinant Anti-Monkeypox B5 Antibody(Clone: MPXV-13)
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| Amount : | 100 µg (1mg/mL) |
| Isotype : | Human IgG1 |
| Purification : | ≥95% monomer by analytical SEC |
| Content : | 1.0 mg/ml . This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Storage condition : | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -70°C. Avoid Repeated Freeze Thaw Cycles. |
| Alternative Name : | MPXV |
| Immunogen Information : | Sequenced from PBMCs from a donor who had recovered from a naturally-occurring MPXV infection |
Expression Host : HEK-293
Reactivity Species : Vaccinia,Variola,Cowpox,Monkeypox,Virus
Specificity : MPXV-13 reacts to B5, an EV surface antigen. This antibody also reacts to VACV antigen and lysate, CPXV lysate, MPXV lysate, and VARV antigen and lysate. MPXV-13 weakly binds to VACV purified antigen, VACV and MPXV virus-infected cell lysates, and strongly binds VARV purified antigen and CPXV virus-infected cell lysate. MPXV-13 neutralizes VACV EV plus complement (+C’) but not MV, MV+C’, or EV. MPXV-13 also binds to CPXV EV+C’ but not EV. MPXV-13 does not neutralize MPXV MV, MV+C’, EV, or EV+C’.
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