Rat Anti-Mouse Ly-6C
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| Amount : | 0.5 mg |
| Isotype : | Rat IgG2c, kappa |
| Content : | 0.5 mg/ml, 1.0 ml, Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added |
| Storage condition : | Store at 2-8°C |
| Subcellular location: | Cell membrane |
| Post transnational modification: | Sumoylated on Lys-266 upon dimerization with CLOCK. Predominantly conjugated to poly-SUMO2/3 rather than SUMO1 and the level of these conjugates undergo rhythmic variation, peaking at CT9-CT12. Sumoylation localizes it exclusively to the PML body and promotes its ubiquitination in the PML body, ubiquitin-dependent proteasomal degradation and the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer. |
| Tissue Specificity: | Expressed in liver and testis (at protein level). |
| BioGrid: | 198207. 17 interactions. |
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