Rat Anti-Mouse BP-1
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| Amount : | 0.5 mg |
| Isotype : | Rat IgG1, kappa |
| Content : | 0.5 mg/ml, 1.0 ml, Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added |
| Storage condition : | Store at 2-8°C |
| Subcellular location: | Membrane |
| Post transnational modification: | Phosphorylation of Thr-51 by MAPK14 and MAPK11, and at Thr-53 by MAPK1/ERK2, MAPK3/ERK1, MAPK11, MAPK12 and MAPK14 in response to external stimulus like insulin causes increased transcriptional activity (By similarity). Phosphorylated by PLK3 following hyperosmotic stress. Also phosphorylated and activated by JNK and CaMK4 (By similarity). Phosphorylation at Ser-44, Thr-55 and Ser-103 activates its transcriptional activity (By similarity). ATM-mediated phosphorylation at Ser-472 and Ser-480 stimulates its function in DNA damage response. Phosphorylation at Thr-51 or Thr-53 enhances its histone acetyltransferase (HAT) activity. |
| Tissue Specificity: | Early B-lineage cells and certain stromal cell of hemopoietic tissues. Also expressed by capillary endothelial cells, placenta, and epithelial cells of the intestine and proximal renal tubules. |
| BioGrid: | 198233. 15 interactions. |
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