Rat Anti-Human Caspase-8
Figure 1: Total cell lysates from Jurkat cells were incubated with STS, resolved by electrophoresis, transferred to PVDF membrane, and probed with Rat Anti-Human Caspase-8 . Proteins were visualized using Goat Anti-Rat IgM-HRP secondary antibody and chemiluminescent detection.
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| Amount : | 0.1 mg |
| Isotype : | Rat IgM, kappa |
| Content : | 1.0 mg/ml, 0.1 ml, Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added |
| Storage condition : | Store at 2-8°C |
| Subcellular location: | Cytoplasm |
| Post transnational modification: | Phosphorylation on Ser-387 during mitosis by CDK1 inhibits activation by proteolysis and prevents apoptosis. This phosphorylation occurs in cancer cell lines, as well as in primary breast tissues and lymphocytes. |
| Tissue Specificity: | Isoform 1, isoform 5 and isoform 7 are expressed in a wide variety of tissues. Highest expression in peripheral blood leukocytes, spleen, thymus and liver. Barely detectable in brain, testis and skeletal muscle. |
| BioGrid: | 107291. 153 interactions. |
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