Polyclonal Antibody to Vav (Phospho-Tyr174)
Figure 1: Western blot analysis of extracts from Jurkat cells untreated or treated with H2O2 using Vav(Phospho-Tyr174) Antibody 35-1136 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation
Predicted MW: 95kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Post transnational modification: | Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS) (By similarity). Phosphorylated by FYN. |
| Tissue Specificity: | Widely expressed in hematopoietic cells but not in other cell types. |
| BioGrid: | 113252. 88 interactions. |
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