Polyclonal Antibody to UNC93B
Fig-1: Western blot analysis of UNC93B . Anti- UNC93B antibody (11-3004) was used at 4 µg/ml on Heart.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.
Western blot analysis: 4-6 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Endoplasmic reticulum membrane, Endosome, Lysosome, Cytoplasmic vesicle |
| Post transnational modification: | N-glycosylated. |
| Tissue Specificity: | Expressed in plasmocytoid dendritic cells (at protein level). Highly expressed in antigen-presenting cells. Expressed in heart, and at lower level in kidney. Expressed at low level in other tissues. |
| BioGrid: | 123557. 33 interactions. |
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