Polyclonal Antibody to Twistnb
Fig-1: Expression analysis of Twistnb. Anti-Twistnb antibody (11-10040) was used at 1 µg/ml on (1) HCT-116 and (2) h Kidney lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
Twistnb is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. This protein contains 2 potential nuclear localization signals in the C terminus and shares 72% sequence identity with the mouse orthologs. Twistnb has highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Tissue Specificity: | Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. |
| BioGrid: | 128759. 21 interactions. |
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