Polyclonal Antibody to TRH-R
Fig-1: Western blot analysis of TRH-R. Anti-TRH-R antibody (11-8021) was used at 1 µg/ml on T98G lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
TRH-R (Thyrotropin-releasing hormone (TRH) receptors are Gq/11-protein-coupled receptors) is a member of G-protein coupled receptor 1 family. This is a thyrotropin-releasing hormone receptor. When it binds to TRH, it activates the inositol phospholipid-calcium-protein kinase C transduction pathway. TRH-R also interacts with ACP2acid phosphatase 2. Its expression found mainly in cerebrum, testis during developmental stage. Literature suggests that endogenous TRH and TRH receptor play an important role of a neurotransmission modulation in the brain to control emotional and mental functions.
Western blot analysis: 1-3 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| BioGrid: | 113052. 2 interactions. |
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