Polyclonal antibody to TRAIP (TRIP)

Product code: 20-1103

Clonality : Polyclonal
Application : IP, IHC, WB
Reactivity : Human

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Size
Price
50 µl
$260.00 

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Shipping Info:

Order now and get it on Tuesday July 23, 2024

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Format : Sera
Amount : 50 µl
Isotype : Rabbit IgG
Content : 50 µl sera
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : TRAIP
Gene ID : 10293
Uniprot ID : Q9BWF2
Alternative Name : TRAIP, RNF206, TRIP
Immunogen Information : A synthetic peptide of human TRIP ( amino acids 294-313 ESPAPVEVNLKLRRPSFRDD) was used as immunogen for this antibody

TRIP (TRAF-interacting protein),also known as TRAIP is a component of receptor-TRAF signaling complexes. Structurally it contains an N-terminal RING finger motif and a putative coiled-coil domain and composed of 469amino acid approximately. TRIP has been shown to associate with TRNFR2 or CD30 signaling complexes through its interaction with TRAF proteins and inhibit TRAF2-mediated NF-kB activation. The recruitment of different TRAFs and TRAF associated proteins like TRIP to receptor complexes can help regulate and provide specificity to the intracellular signals triggered by the cell surface receptors.

WB: 1:1000-1:2000, IHC (paraffin): 1:1000-1:5000, IHC (frozen): Users should optimize, IP: 1:50-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Cytoplasm, Nucleus, Nucleus
Post transnational modification: Autoubiquitinated.
BioGrid: 115581. 37 interactions.
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