Polyclonal Antibody to Tis7
Fig-1: Western blot analysis of Tis7. Anti-Tis7 antibody (11-4016) was used at 4 µg/ml on Testis lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Tissue Specificity: | Expressed in a variety of tissues. |
| BioGrid: | 109697. 16 interactions. |
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