Polyclonal Antibody to Syndecan-4
Fig-1: Western blot analysis of Syndecan-4, Sdc4 . Anti-Syndecan-4, Sdc4 antibody (11-4014) was used at 2 µg/ml on (1) MCF-7 and (2) A549 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Syndecan-4 (SDC4) belongs to a family of transmembrane proteoglycans, which is capable of modulating cell behavior through their capacity to act as cell surface coreceptors for a variety of heparin binding proteins. Syndecan-4 appears to be directly involved in regulating platelet aggregation as anti-syndecan-4 antibody augments platelet aggregation.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane, Secreted |
| Post transnational modification: | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3 (By similarity). |
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