Polyclonal Antibody to Syndecan-4

Fig-1: Western blot analysis of Syndecan-4, Sdc4 . Anti-Syndecan-4, Sdc4 antibody (11-4014) was used at 2 µg/ml on (1) MCF-7 and (2) A549 lysates.

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Product code: 11-4014

Clonality :	Polyclonal
Application :	WB
Reactivity :	Human

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Format :	Purified
Amount :	100 µg
Isotype :	Rabbit IgG
Purification :	Protein A Chromatography
Content :	25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	SDC4
Gene ID :	6385
Uniprot ID :	P31431
Alternative Name :	Amphiglycan, Ryudocan core protein
Immunogen Information :	Full length recombinant Syndecan-4 protein was used as the immunogen for this antibody.

Syndecan-4 (SDC4) belongs to a family of transmembrane proteoglycans, which is capable of modulating cell behavior through their capacity to act as cell surface coreceptors for a variety of heparin binding proteins. Syndecan-4 appears to be directly involved in regulating platelet aggregation as anti-syndecan-4 antibody augments platelet aggregation.

Western blot analysis: 2-4 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Membrane, Secreted
Post transnational modification:	Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3 (By similarity).