Polyclonal Antibody to Synaptotagmin 1/2 (Phospho-Thr202/199)
Figure 1: Immunofluorescence staining of methanol-fixed Hela cells using Synaptotagmin 1/2 (Phospho-Thr202/199) Antibody 35-1196 .
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Format : | Purified |
Amount : | 100 µl |
Isotype : | Rabbit IgG |
Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Gene : | SYT1 |
Gene ID : | 6857 |
Uniprot ID : | P21579/Q89I0 |
Alternative Name : | SYT1/2, SytI/II, Synaptotagmin I/II, P65, SYT |
Immunogen Information : | Peptide sequence around phosphorylation site of threonine 202/199 (R-K-T(p)-L-N) derived from Human Synaptotagmin 1/2. |
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18(5):1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18(12):4957-68.
Predicted MW: 46kd, Immunofluorescence: 1:100~1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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