Polyclonal Antibody to Smad1/Smad5/Smad8
Figure 1: Western blot analysis of extracts from 3T3 cells using Smad1/Smad5/Smad8 Antibody 35-1852 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | 1.0 mg/ml,100 µl |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Alternative Name : | Mad-related protein 1, SMAD 1, hSMAD1, Transforming growth factor-beta-signaling protein 1 |
| Immunogen Information : | Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8. |
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
Predicted MW: 60kd, Western blotting: 1: 500~1: 1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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