Polyclonal Antibody to SC1
Fig-1: Expression analysis of SC1. Anti-SC1 antibody (11-12014) was used at 1 µg/ml on (1) h Spleen and (2) PC3 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
SC1is a putative transactivating factor, with expression beginning at the late G1/S boundary in dividing cells. It contains a FHA association (Forkhead) domain, which may serve as a nuclear signaling domain or as a phosphoprotein binding domain.SC1is expressed in mouse and human islets, with increasing mRNA expression in nondiabetic obesity. The expression of SC1 is correlated with Beta-cell mass expansion, suggesting that it may be a transcriptional regulator of Beta-cell mass.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| BioGrid: | 112801. 13 interactions. |
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