Polyclonal Antibody to SAPK/JNK (Phospho-Thr183)

Product code: 35-1231

Clonality : Polyclonal
Application : WB, IHC
Reactivity : Human, Mouse, Rat

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : MAPK9
Gene ID : 5601
Uniprot ID : P45984/P53779
Alternative Name : JNK2
Immunogen Information : Peptide sequence around phosphorylation site of threonine 183 (M-M-T(p)-P-Y) derived from Human SAPK/JNK.
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Ferrer, et al. (2003) Neuropathology & Applied Neurobiology 29: 23 Zhonghong Guan, et al. (1999) J Biol Chem, Vol. 274: 36200-36206 D.Margriet Ouwens1, et al. (2002)The EMBO Journal 21: 3782

Predicted MW: 46 54 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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