Polyclonal Antibody to S1P3 receptor, Edg-3
Fig-1: Western blot analysis of S1P3 receptor, Edg-3. Anti- S1P3 receptor, Edg-3 antibody (11-10017) was used at 4 µg/ml on Liver lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
S1PR3 (sphingosine-1phosphate receptor3) is a vascular barrier regulatory member of the S1P family of receptors (S1PR15) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury). S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Tissue Specificity: | Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver. |
| BioGrid: | 108227. 3 interactions. |
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