Polyclonal Antibody to RuvB-like 1
Fig-1: Western blot analysis of RuvB-like 1. Anti-RuvB-like 1 antibody (11-8079) was used at 2 µg/ml on (1) THP1 and (2) 293 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
RuvB-like 1 belongs to the family of AAA+ ATPases that associate with chromatin-remodelling complexes and have important roles in transcriptional regulation, the DNA damage response, telomerase activity and cellular transformation. It plays important roles in essential signaling pathways such as the c-Myc and Wnt pathways in chromatin remodeling, transcriptional and developmental regulation, and DNA repair and apoptosis.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus matrix, Nucleus, Cytoplasm, Membrane, Cytoplasm |
| Tissue Specificity: | Ubiquitously expressed with high expression in heart, skeletal muscle and testis. |
| BioGrid: | 114166. 228 interactions. |
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