Polyclonal Antibody to ROR alpha
Figure-1: Western blot analysis of ROR alpha. Anti-ROR alpha antibody (11-4077) was used at 1 µg/ml on h Pancrease lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | RORA |
| Gene ID : | 6095 |
| Uniprot ID : | P35398 |
| Alternative Name : | Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, NR1F1, RZRA |
| Immunogen Information : | A partial length recombinant ROR alpha protein (amino acids 220-440) was used as the immunogen for this antibody. |
Recommended dilutions: WB: 1-2 µg/ml. However, this need to be optimized based on the research applications.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Post transnational modification: | Isoform 1: monomethylated at Lys-38 by EZH2, this creates a degron recognized by a DCX (DDB1-DCAF1/VPRBP-CUL4A-RBX1) E3 ubiquitin ligase complex. |
| Tissue Specificity: | Widely expressed in a number of tissues. Expressed in both regulatory T-cells (Treg) and effector T-cells (Teff). |
| BioGrid: | 112022. 24 interactions. |
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