Polyclonal Antibody to ROR alpha

Product code: 11-4077

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $100.00 

  • $270.00 

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Shipping Info:

Order now and get it on Wednesday December 25, 2024

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : RORA
Gene ID : 6095
Uniprot ID : P35398
Alternative Name : Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, NR1F1, RZRA
Immunogen Information : A partial length recombinant ROR alpha protein (amino acids 220-440) was used as the immunogen for this antibody.

Recommended dilutions: WB: 1-2 µg/ml. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Post transnational modification: Isoform 1: monomethylated at Lys-38 by EZH2, this creates a degron recognized by a DCX (DDB1-DCAF1/VPRBP-CUL4A-RBX1) E3 ubiquitin ligase complex.
Tissue Specificity: Widely expressed in a number of tissues. Expressed in both regulatory T-cells (Treg) and effector T-cells (Teff).
BioGrid: 112022. 24 interactions.
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