Polyclonal Antibody to PLC- Gamma2 (phospho-Tyr1217)

Figure 1: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLC-g2(Phospho-Tyr1217) Antibody 35-1315 (left) or the same antibody preincubated with blocking peptide(right).

Polyclonal Antibody to PLC- Gamma2 (phospho-Tyr1217)

Roll over image to zoom in

Product code: 35-1315

Clonality :	Polyclonal
Application :	IHC
Reactivity :	Human, Mouse, Rat

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Write a review for this product on BioCompare

Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	100 µl
Isotype :	Rabbit IgG
Content :	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	PLCG2
Gene ID :	5336
Uniprot ID :	P16885
Alternative Name :	PLC-IV, PLC-gamma2, Phospholipase C-gamma-2
Immunogen Information :	Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from Human PLCg2.

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Predicted MW: 150kd, Immunohistochemistry: 1:50~1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Post transnational modification:	Phosphorylated on tyrosine residues by CSF1R (By similarity). Phosphorylated on tyrosine residues by BTK and SYK; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Phosphorylation leads to increased phospholipase activity.
BioGrid:	111352. 45 interactions.