Polyclonal Antibody to OCT1
Figure 1: Western blot analysis of extracts from JK, HepG2 and 293 cells using Oct-1 Antibody 35-1842 .
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Shipping Info:
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. Prefontaine G.G., Walther R., Giffin W. J. Biol. Chem. 274:26713-26719(1999) Mahajan S.S., Wilson A.C. Mol. Cell. Biol. 20:919-928(2000)
Predicted MW: 90kd, Western blotting: 1:500~1:1000, Immunofluorescence?1:100~1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Post transnational modification: | Phosphorylated by PRKDC. |
| Tissue Specificity: | Ubiquitous. Isoform 2 is lymphocyte-specific. |
| BioGrid: | 111447. 65 interactions. |
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