Polyclonal antibody to NALP4 (PAN-2)

Product code: 20-1079

Clonality : Polyclonal
Application : IP, IHC, WB
Reactivity : Human

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Size
Price
50 µl
$260.00 

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Shipping Info:

Order now and get it on Tuesday November 19, 2024

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Format : Sera
Amount : 50 µl
Isotype : Rabbit IgG
Content : 50 µl sera
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : NLRP4
Gene ID : 147945
Uniprot ID : Q96MN2
Alternative Name : NLRP4, NALP4, PAN2, PYPAF4, RNH2
Immunogen Information : A synthetic peptide of human NALP4/PAN2/PYPAF4 (amino acids 139-157 FAPKETGKQPRTVIIQGPQ) was used as immunogen for this antibody

This antibody recognizes NALP4; human NALP4 is a 994 amino acid protein. NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.

WB: 1:1000-1:2000, IHC (paraffin): 1:1000-1:5000, IHC (frozen): Users should optimize, IP: 1:50-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

BioGrid: 127102. 6 interactions.
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