Polyclonal Antibody to Met (Ab-1349)

Product code: 35-1566

Clonality : Polyclonal
Application : WB
Reactivity : Human, Mouse, Rat

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : IRS1
Gene ID : 3667
Uniprot ID : P35568
Alternative Name : HGF receptor, HGF-SF receptor, Met proto-oncogene tyrosine kinase, c-met, kinase Met
Immunogen Information : Peptide sequence around aa.1347~1351 (E-H-Y-V-H) derived from Human Met.
Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Predicted MW: 156kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Post transnational modification: Ubiquitinated by the Cul7-RING(FBXW8) complex in a mTOR-dependent manner, leading to its degradation: the Cul7-RING(FBXW8) complex recognizes and binds IRS1 previously phosphorylated by S6 kinase (RPS6KB1 or RPS6KB2).
BioGrid: 109874. 67 interactions.
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