Polyclonal Antibody to KLF15
Fig-1: Western blot analysis of KLF15. Anti-KLF15 antibody (11-8070) was used at 4 µg/ml on 1) Heart, 2) 3T3 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
KLF15 (Kruppel-like factor 15) is a 43 kDa protein belonging to Kruppel family of transcription regulators. KLF15 can either contribute in expression or suppression of specific genes. KLF15 contains three zinc-finger motifs. KLF15 interacts with the GA element of the kidney chloride channel protein (CLCNKA) promoter. KLF15 also regulates the cardiac ion channel expression thereby controlling the rhythmic expression of potassium channel-interacting protein-2 (KChIP). KLF18 is highly expressed in liver, heart, skeletal muscle and kidney.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Tissue Specificity: | Highly expressed in liver, skeletal muscle, and kidney. Expressed in cardiomyocytes. Expression is highly reduced in cardiac tissue of patients with non-ischemic cardiomyopathy and aortic aneurysm, and in glomerular disease. Not expressed in bone marrow or lymphoid tissues. |
| BioGrid: | 118818. 15 interactions. |
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