Polyclonal Antibody to Keratin 19

Figure 1: Western blot analysis of extract from rat and mouse brain tissue using Keratin 19 Antibody 35-1785

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Figure 1: Western blot analysis of extract from rat and mouse brain tissue using Keratin 19 Antibody 35-1785

Figure 2: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using Keratin 19 Antibody 35-1785 (left) or the same antibody preincubated with blocking peptide (right).

Figure 3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using Keratin 19 Antibody 35-1785 (left) or the same antibody preincubated with blocking peptide (right).

Product code: 35-1785

Clonality :	Polyclonal
Application :	WB, IHC
Reactivity :	Human, Mouse, Rat

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	100 µl
Isotype :	Rabbit IgG
Content :	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	KRT19
Gene ID :	3880
Uniprot ID :	P08727
Alternative Name :	K19, K1CS, MGC15366, KRT19, CK19
Immunogen Information :	Peptide sequence around aa.392~396(N-N-L-S-A) derived from Human Keratin 19.

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Stone M.R., O'Neill A., Catino D., Bloch R.J. Mol. Biol. Cell 16:4280-4293(2005)

Predicted MW: 41kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Tissue Specificity:

Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

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