Polyclonal Antibody to IGFBP-3
Figure 1: Western blot analysis of extracts from various cells using IGFBP-3 Antibody 35-1839 .
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Shipping Info:
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Roghani M., Segovia B., Whitechurch O., Binoux M.Growth Regul. 1:125-130(1991) Ikonen M., Liu B., Hashimoto Y., Ma L. Cohen P.Proc. Natl. Acad. Sci. U.S.A. 100:13042-13047(2003) Zhou W., Ross M.M., Tessitore A. J. Proteome Res. 8:5523-5531(2009)
Predicted MW: 24-41kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | Phosphorylated by FAM20C in the extracellular medium. |
| Tissue Specificity: | Expressed by most tissues. Present in plasma. |
| BioGrid: | 109707. 18 interactions. |
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