Polyclonal Antibody to hnRNPK
Fig-1: Western blot analysis of hnRNPK. Anti-hnRNPK antibody (11-1018) was used at 1 µg/ml on (1) 293 and (2) A549 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
The heterogeneous nuclear ribonucleoprotein K (hnRNPK) is a multifunctional docking protein that integrates several signal transduction pathways with a variety of gene expression regulatory mechanisms including transcription and translation by binding to chromatin and RNA, respectively. It has been shown to directly bind and regulate expression of multiple promoters including c-Myc, c-Src, thymidine kinase 1, androgen receptor, eukaryotic translation initiation factor 4E, and p53 target genes.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus, Cell projection |
| Post transnational modification: | O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner. |
| BioGrid: | 109431. 381 interactions. |
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