Polyclonal Antibody to Her3/ErbB3 (Ab-1289)
Figure 1: Immunofluorescence staining of methanol-fixed MCF cells using Her3/ErbB3(Ab-1289) Antibody 35-1726 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Binds and is activated by neuregulins and NTAK.
Predicted MW: 185kd, Immunofluorescence: 1:100~1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | Autophosphorylated (PubMed:20351256). Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). |
| Tissue Specificity: | Epithelial tissues and brain. |
| BioGrid: | 108377. 187 interactions. |
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