Polyclonal Antibody to GPR83
Fig-1: Expression analysis of GPR83. Anti-GPR83 antibody (11-4003) was used at 1 µg/ml on (1) PC3 and (2) HCT-116 lysates.
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Format : | Purified |
Amount : | 100 µg |
Isotype : | Rabbit IgG |
Purification : | Protein A Chromatography |
Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
GPR83 (also known as GIR/ GPR72) is an orphan G protein-coupled receptor highly expressed in brain and thymus. It is most homologous to the tachykinin and neuropeptide Y (NPY) receptors. GPR83 is selectively up-regulated by both murine and human CD4(+)CD25(+) regulatory T cells (Treg) cells and is involved in the induction of CD4(+)Foxp3(+) Tregs in the course of an ongoing immune response.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cell membrane |
Tissue Specificity: | Brain specific. |
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