Polyclonal Antibody to Glutamine Synthetase
Figure 1: Western blot analysis of extracts from Rat and Mouse brain tissue and C6 cells using Glutamine Synthetase Antibody 35-1818 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner . Essential for proliferation of fetal skin fibroblasts. "Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase." Boksha I.S., Schonfeld H.J., Langen H. Biokhimiia 67:1012-1020(2002) "Glutamine synthetase is essential for proliferation of fetal skin fibroblasts." Vermeulen T., Goerg B., Vogl T. Arch. Biochem. Biophys. 478:96-102(2008)
Predicted MW: 42kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Microsome, Mitochondrion, Cell membrane |
| Post transnational modification: | Ubiquitinated by ZNRF1. |
| Tissue Specificity: | Expressed in endothelial cells. |
| BioGrid: | 109014. 43 interactions. |
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