Polyclonal Antibody to GluR1

Product code: 35-1761

Clonality : Polyclonal
Application : WB
Reactivity : Rat, Mouse, Human

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  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : GRIA1
Gene ID : 2890
Uniprot ID : P42261
Alternative Name : GLR1, GLUH1, GRIA1, GluR-1, GluR-A
Immunogen Information : Peptide sequence around aa. 831~835 (K-S-R-S-E) derived from Human GluR1

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Predicted MW: 110kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Endoplasmic reticulum membrane, Cell junction, Cell junction, Cell projection, Cell projection, Early endosome membrane, Recycling endosome membrane
Post transnational modification: Phosphorylated at Ser-645. Phosphorylated at Ser-710 by PKC. Phosphorylated at Ser-849 by PKC, PKA and CAMK2. Phosphorylated at Ser-863 by PKC, PKA and PRKG2.
Tissue Specificity: Widely expressed in brain.
BioGrid: 109147. 23 interactions.
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