Polyclonal Antibody to Gbp1
Fig-1: Western blot analysis of Gbp1. Anti- Gbp1 antibody (11-3031) was used at 4 µg/ml on 1) U87, 2) Jurkat and 3) Hela lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Interferon-induced guanylate-binding protein 1 in humans is encoded by the GBP1 gene belongs to the dynamin superfamily of large GTPases and induced by interferons. GBP1 hydrolyzes GTP to GMP in two consecutive cleavage reactions and also exhibits antiviral activity against influenza virus. Diseases associated with GBP1 include pseudo pseudo hypoparathyroidism and aneurysmal bone cysts. It is widely expressed on central nervous system, mammary gland, skeletal muscle, skin, small intestine, stomach, etc.
Western blot analysis: 4-6 µg/ml, Immunohistochemical analysis: 20 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Golgi apparatus membrane, Cell membrane, Secreted |
| Post transnational modification: | Isoprenylation is required for proper subcellular location. |
| BioGrid: | 108903. 19 interactions. |
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