Polyclonal Antibody to GATA1 (Ab-310)

Figure 1: Western blot analysis of extracts from K562 and HT29 cells using GATA1(Ab-310) Antibody 35-1398 .

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Product code: 35-1398

Clonality :	Polyclonal
Application :	WB
Reactivity :	Human, Mouse, Rat

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Download TDS MSDS

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	100 µl
Isotype :	Rabbit IgG
Content :	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	GATA1
Gene ID :	2623
Uniprot ID :	P15976
Alternative Name :	GAT1, GATA1, GF-1, NF-E1
Immunogen Information :	Peptide sequence around aa.308~312 (K-A-S-G-K) derived from Human GATA1.

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Kadri Z, et al.(2005)Mol Cell Biol 2005 Sep; 25(17): 7412-22.

Predicted MW: 43kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Nucleus
Post transnational modification:	Acetylated at 2 conserved lysine-rich motifs by CREBBP in vitro. Acetylation does not affect DNA-binding in vitro but is essential to induce erythroid differentiation and for binding chromatin in vivo (By similarity). Acetylated on Lys-233, Lys-245 Lys-246 by EP300.
Tissue Specificity:	Erythrocytes.
BioGrid:	108893. 61 interactions.