Polyclonal Antibody to GAP43
Figure-1: Immunofluorescent analysis of cortical neuron-glial cell culture from E20 rat stained with chicken pAb to GAP43,(34-1038), dilution 1:2,000 in green, and costained with rabbit pAb to α-II spectrin, (34-1109), dilution 1:1,000 in red. The blue is DAPI staining of nuclear DNA. GAP43 antibody labels protein expressed in the axonal membrane and synapses of neuronal cells, while the spectrin antibody stains the submembraneous cytoskeleton of axons and dendrites.
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| Format : | Conc. IgY prep. |
| Amount : | 100 µl |
| Isotype : | Chicken, IgY |
| Content : | Antibody is supplied as an aliquot of IgY preparation |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | GAP43 |
| Gene ID : | 2596 |
| Uniprot ID : | P17677 |
| Alternative Name : | Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 |
| Immunogen Information : | C-terminal peptide of rat and mouse GAP43, which is KEDPEADQEHA, to which an N terminal Cys residue was added to allow chemical coupling to KLH |
WB: 1:1,000-1-:5,000. IF/IHC: 1:500-1:1,000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Cell projection, Cell junction, Cell projection |
| Post transnational modification: | Palmitoylation by ARF6 is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2. |
| BioGrid: | 108867. 27 interactions. |
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