Polyclonal Antibody to Formin-like protein 2
Fig-1: Western blot analysis of Formin-like protein 2. Anti-Formin-like protein 2 antibody (11-10008) was used at 4 µg/ml on HCT-116 lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Formin-like protein 2/FHOD1 (formin homology 2 domain containing 1) acts as a capping and bundling protein. In cells, active FHOD1 stimulates the formation of ventral stress fibers. FHOD1 is mainly located at the intercalated disc, the special type of cell-cell contact between cardiomyocytes (25125170).FHOD1 promotes the formation of short actin filaments and transiently associates with transverse arcs, thus providing tight temporal and spatial control of the formation and turnover of transverse arcs into mature ventral stress fibers during dynamic cell behavior (24481812).
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Cytoplasm, Cell projection |
| Post transnational modification: | Phosphorylated by ROCK1. |
| Tissue Specificity: | Ubiquitous. Highly expressed in spleen. |
| BioGrid: | 118877. 33 interactions. |
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