Polyclonal Antibody to  Estrogen Receptor alpha

Product code: 11-7577

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $100.00 

  • $270.00 

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Shipping Info:

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : ESR1
Gene ID : 2099
Uniprot ID : P03372
Alternative Name : ESR,  NR3A1, ESR1
Immunogen Information : A partial length recombinant Estrogen receptor protein (amino acids 110-360 ) was used as the immunogen for this antibody.

Western blot analysis: 1-2 µg/ml

This antibody detects ~46 kDa band. The size corresponds from OMIM, the right size is ~66 kDa

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Golgi apparatus, Cell membrane
Post transnational modification: Palmitoylated by ZDHHC7 and ZDHHC21. Palmitoylation is required for plasma membrane targeting and for rapid intracellular signaling via ERK and AKT kinases and cAMP generation, but not for signaling mediated by the nuclear hormone receptor.
Tissue Specificity: Widely expressed. Isoform 3 is not expressed in the pituitary gland.
BioGrid: 108403. 738 interactions.
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