Polyclonal Antibody to Elk1(Phospho-Thr417)

Product code: 35-1037

Clonality : Polyclonal
Application : IHC, IF
Reactivity : Human, Mouse, Rat

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : ELK1
Gene ID : 2002
Uniprot ID : P19419
Alternative Name : ELKV
Immunogen Information : Peptide sequence around phosphorylation site of threonine 417(L-S-T(p)-P-V) derived from Human Elk1.
Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element. Yang S.-H., Sharrocks A.D.EMBO J. 24:2161-2171(2005) Zhang L., Yang S.H., Sharrocks A.D.Mol. Cell. Biol. 27:2861-2869(2007)

Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Post transnational modification: On mitogenic stimulation, phosphorylated on C-terminal serine and threonine residues by MAPK1. Ser-383 and Ser-389 are the preferred sites for MAPK1. In vitro, phosphorylation by MAPK1 potentiates ternary complex formation with the serum responses factors, SRE and SRF. Also phosphorylated on Ser-383 by MAPK8 and/or MAKP9. Phosphorylation leads to loss of sumoylation and restores transcriptional activator activity. Phosphorylated and activated by CAMK4, MAPK11, MAPK12 and MAPK14. Upon bFGF stimulus, phosphorylated by PAK1 (By similarity).
Tissue Specificity: Lung and testis.
BioGrid: 108317. 28 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products