Polyclonal Antibody to EGFR (Ab-693)

Figure 1: Western blot analysis of extracts from HUVEC and MDA cells using EGFR(Ab-693) Antibody 35-1532 .

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Product code: 35-1532

Clonality :	Polyclonal
Application :	WB
Reactivity :	Human, Mouse, Rat

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	100 µl
Isotype :	Rabbit IgG
Content :	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	EGFR
Gene ID :	1956
Uniprot ID :	P00533
Alternative Name :	Receptor tyrosine-protein kinase ErbB-1, ERBB1
Immunogen Information :	Peptide sequence around aa.691~695 (P-L-T-P-S) derived from Human EGFR.

Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia Doherty JK, et al. (1999) Proc Natl Acad Sci U S A; 96(19): 10869-10874 Wu TT, et al. (1998) Mol Biol Cell; 9(7): 1661-1674 O

Predicted MW: 175kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Secreted
Post transnational modification:	Methylated. Methylation at Arg-1199 by PRMT5 stimulates phosphorylation at Tyr-1197.
Tissue Specificity:	Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.
BioGrid:	108276. 1217 interactions.