Polyclonal Antibody to DKK1
Fig-1: Western blot analysis of DKK1. Anti-DKK1 antibody (11-7503) was used at 4 µg/ml on MCF-7 lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
DKK1 is a 68 kDa protein of the Dickkopf family. DKK1 is a secreted protein with two cysteine-rich domains which help in interaction with LRP5 and LRP6 thereby inhibiting the Wnt signaling pathway. DKK1 regulates embryonic development in vertebrates. DKK1 is over expressed in bone marrow and peripheral blood in patients with multiple myeloma. DKK1 is also associated with malignant myeloma. DKK1 is highly expressed in placenta.
Western blot analysis: 4-6 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Tissue Specificity: | Placenta. |
| BioGrid: | 116599. 15 interactions. |
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