Polyclonal antibody to DEDD2 ( DED2/Flame-3 )

Product code: 20-1062

Clonality : Polyclonal
Application : IP, IHC, WB
Reactivity : Human

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Size
Price
50 µl
$260.00 

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Shipping Info:

Order now and get it on Tuesday December 24, 2024

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Format : Sera
Amount : 50 µl
Isotype : Rabbit IgG
Content : 50 µl sera
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : DEDD2
Gene ID : 162989
Uniprot ID : Q8WXF8
Alternative Name : DEDD2, FLAME3, PSEC0004
Immunogen Information : A synthetic peptide of DEDD2 (DED2/Flame-3) protein (amino acids 175-193 APAAPQQQSEPARPSSEGK) was used as immunogen for this antibody

This antibody recognizes DEDD2/Flame-3; human DED2/Flame-3 is a 326 amino acid protein. This protein belongs to a family of single DED-containing proteins that is targeted to the nucleus. Several DED-containing proteins are involved in the regulation of apoptosis through their interactions with DED-containing caspases. It is thought that DEDD2 and its closely related homologue DEDD may mediate cell death by binding to the DED-containing caspases -8 and -10, and targeting them to the nucleus following death receptor induced apoptosis. However, the function of DEDD2 and DEDD remain to be fully elucidated, and they may also have roles in cellular processes other than apoptosis.

WB: 1:1000-1:2000, IHC (paraffin): 1:1000-1:5000, IHC (frozen): Users should optimize, IP: 1:50-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
BioGrid: 127838. 13 interactions.
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