Polyclonal Antibody to CYP1B1
Fig-1: Western blot analysis of CYP1B1. Anti-CYP1B1 antibody (11-1003) was used at 4 µg/ml on A549 lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
CYP1B1 (Cytochrome P450 1B1) belongs to the CYP450 superfamily of heme-binding mono-oxygenases which catalyze oxidation of various endogenous and exogenous substrates. The expression of Cyp1b1 plays an important role in the modulation of development and functions of the trabecular meshwork (TM). Mutations in Cyp1b1 found in patients with primary congenital glaucoma (PCG).It plays an important role in breast cancer development and progression by bioactivating endogenous estrogens and environmental carcinogens. It is over-expressed at the early stage of NNK-induced lung tumorigenesis.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion |
| Tissue Specificity: | Expressed in many tissues. |
| BioGrid: | 107925. 2 interactions. |
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