Polyclonal Antibody to Connexin 43 (Ab-367)

Product code: 35-1583

Clonality : Polyclonal
Application : WB, IHC
Reactivity : Human, Mouse, Rat

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  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : GJA1
Gene ID : 2697
Uniprot ID : P17302
Alternative Name : CX43, CXA1, CXN-43, Connexin 43, GJA1
Immunogen Information : Peptide sequence around aa. 365~369 (R-A-S-S-R) derived from Human Connexin 43.
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

Predicted MW: 43kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Cell junction, Endoplasmic reticulum
Post transnational modification: S-nitrosylation at Cys-271 is enriched at the muscle endothelial gap junction in arteries, it augments channel permeability and may regulate of smooth muscle cell to endothelial cell communication.
Tissue Specificity: Expressed in the heart and fetal cochlea.
BioGrid: 108964. 64 interactions.
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