Polyclonal Antibody to CDK6 (phospho-Tyr24)
Figure 1: Western blot analysis of extracts from 293 cells untreated(lane 1) or treated with starvation(lane 2) using CDK6(phospho-Tyr24) Antibody 35-1326 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.
Predicted MW: 36kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus, Cell projection, Cytoplasm |
| Post transnational modification: | Thr-177 phosphorylation and Tyr-24 dephosphorylation promotes kinase activity. |
| Tissue Specificity: | Expressed ubiquitously. Accumulates in squamous cell carcinomas, proliferating hematopoietic progenitor cells, beta-cells of pancreatic islets of Langerhans, and neuroblastomas. Reduced levels in differentiating cells. |
| BioGrid: | 107456. 162 interactions. |
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